Description

4-Azaspiro[2.4]Heptane Hemioxalate is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique constrained three-dimensional structure, which is highly sought after for modulating the physicochemical properties and biological activity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry: Used to introduce a rigid, spirocyclic scaffold into lead compounds to improve selectivity, metabolic stability, and binding affinity.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology: Employed as a molecular probe or a core structure in fragment-based drug discovery (FBDD) libraries.
• Academic Research: Utilized in methodological studies and the synthesis of complex natural product analogs or novel heterocyclic systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	4-Azaspiro[2.4]Heptane Hemioxalate
CAS No.	1523571-00-7
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	4-Azaspiro[2.4]heptane, hemioxalate salt; 1-Azaspiro[2.4]heptane hemioxalate; 4-Aza-spiro[2.4]heptane oxalic acid salt (1:0.5); Azaspiroheptane hemioxalate; Spiro[cyclopropane-1,2'-pyrrolidine] hemioxalate; 2-Azabicyclo[2.1.1]hexane hemioxalate (tautomeric form); 4-Azaspiro[2.4]heptane compound with oxalic acid (2:1)
EINECS	Contact for details

Quality Control

Our 4-Azaspiro[2.4]Heptane Hemioxalate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.