Description

2-Oxa-6-Azaspiro[3.4]Octane Hemioxalate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Serves as a starting material for scaling up the production of investigational new drugs under Good Manufacturing Practice (GMP) conditions.
• Proteolysis Targeting Chimera (PROTAC) Development: The spirocyclic structure can be utilized as a linker component in the design of bifunctional degrader molecules.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying biological pathways and target engagement.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3.4]Octane Hemioxalate
CAS No.	1523570-96-8
Molecular Formula	C8H13NO5
Molecular Weight	203.19 g/mol
Synonyms	2-Oxa-6-azaspiro[3.4]octane hemioxalate; 2-Oxa-6-azaspiro[3.4]octane oxalic acid salt (1:0.5); 6-Aza-2-oxaspiro[3.4]octane hemioxalate; 2-Oxa-6-azaspiro[3.4]octane, oxalic acid salt; Spiro[3.4]octane-2,6-diol hemioxalate derivative; 1-Oxa-5-azaspiro[2.4]heptane hemioxalate (alternative numbering); 1523570-96-8
EINECS	Contact for details

Quality Control

Our 2-Oxa-6-Azaspiro[3.4]Octane Hemioxalate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support regulatory filings, and we can supply material that meets specific customer requirements for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.