Description

Ethyl 2-(2-Bromo-6-Fluorophenyl)-2-Oxoacetate is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce key functional groups into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides and pesticides, leveraging its halogenated phenyl ring.
• Material Science Research: Serves as a precursor for the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Ethyl 2-(2-Bromo-6-Fluorophenyl)-2-Oxoacetate
CAS No.	1518047-62-5
Molecular Formula	C10H8BrFO3
Molecular Weight	275.07 g/mol
Synonyms	Ethyl (2-bromo-6-fluorophenyl)oxoacetate; 2-Bromo-6-fluoro-α-oxobenzeneacetic acid ethyl ester; Ethyl 2-bromo-6-fluorobenzoylformate; (2-Bromo-6-fluorophenyl)(oxo)acetic acid ethyl ester; Ethyl α-oxo-2-bromo-6-fluorophenylacetate; Ethyl 2-oxo-2-(2-bromo-6-fluorophenyl)acetate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-(2-Bromo-6-Fluorophenyl)-2-Oxoacetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the stringent requirements for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.