Description

5-(Phenylmethyl)-5-Azaspiro[2.5]Octan-8-One is a high-value, nitrogen-containing spirocyclic compound with the CAS registry number 1506194-41-7. This advanced pharmaceutical intermediate is critical for the synthesis of complex bioactive molecules, offering a unique structural scaffold for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Used in the research and synthesis of new generation pesticides and herbicides, leveraging its spirocyclic architecture.
• Chemical Biology Probes: Employed in the development of molecular probes and tools for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	5-(Phenylmethyl)-5-Azaspiro[2.5]Octan-8-One
CAS No.	1506194-41-7
Molecular Formula	C14H17NO
Molecular Weight	215.29 g/mol
Synonyms	5-Benzyl-5-azaspiro[2.5]octan-8-one; 5-Azaspiro[2.5]octan-8-one, 5-(phenylmethyl)-; 1506194-41-7; 5-Benzyl-5-azaspiro[2.5]octan-8-one; 5-(Benzyl)-5-azaspiro[2.5]octan-8-one; Spiro[2.5]octan-8-one, 5-(phenylmethyl)-5-aza-; 5-Benzyl-5-aza-spiro[2.5]octan-8-one
EINECS	Contact for details

Quality Control

Our 5-(Phenylmethyl)-5-Azaspiro[2.5]Octan-8-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.