Description

5-Bromo-2-Chloro-4-Fluoro-Benzoic Acid Methyl Ester is a high-purity, multi-halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its stable, substituted benzene core.
• Custom Chemical Synthesis: Provides a versatile starting point for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Fluoro-Benzoic Acid Methyl Ester
CAS No.	1502717-31-8
Molecular Formula	C8H5BrClFO2
Molecular Weight	267.48 g/mol
Synonyms	Methyl 5-Bromo-2-Chloro-4-Fluorobenzoate; Benzoic acid, 5-bromo-2-chloro-4-fluoro-, methyl ester; 5-Bromo-2-chloro-4-fluorobenzoic acid methyl ester; 2-Chloro-5-bromo-4-fluorobenzoic acid methyl ester; Methyl 5-bromo-2-chloro-4-fluorobenzoate; 1502717-31-8; Methyl 2-chloro-5-bromo-4-fluorobenzoate
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.