Description

tert-Butyl 6-Aminopyridine-2-Carboxylate is a high-purity, protected aminopyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create sophisticated nitrogen-containing ligands for transition metal catalysis.
• Material Science Research: Monomer or functionalizing agent in the development of advanced polymers and functional organic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects.

Basic Information

Item	Detail
Product Name	tert-Butyl 6-Aminopyridine-2-Carboxylate
CAS No.	1499890-31-1
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	6-Amino-2-pyridinecarboxylic acid tert-butyl ester; tert-Butyl 6-amino-2-pyridinecarboxylate; 2-Pyridinecarboxylic acid, 6-amino-, 1,1-dimethylethyl ester; 6-Aminopicolinic acid tert-butyl ester; 2-(tert-Butoxycarbonyl)-6-aminopyridine; Boc-6-aminopicolinate; t-Butyl 6-aminopicolinate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Aminopyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP development and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.