Description

5-Bromospiro[Cyclopropane-2,1-Indane]-1-Carboxylic Acid is a high-value, multifunctional spirocyclic building block used in advanced organic synthesis. Its unique bridged structure, incorporating a bromine substituent and a carboxylic acid group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in the development of chemical tools for studying biological systems.
• Catalyst & Ligand Development: The spirocyclic framework can be utilized to create novel chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, functionalized spiro compounds.

Basic Information

Product Name	5-Bromospiro[Cyclopropane-2,1-Indane]-1-Carboxylic Acid
CAS No.	1499315-74-0
Molecular Formula	C12H11BrO2
Molecular Weight	267.12 g/mol
Synonyms	5-Bromo-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylic acid; 5-Bromospiro[cyclopropane-2,1'-indene]-1'-carboxylic acid; 5-Bromo-1H-cyclopropa[a]indene-1-carboxylic acid; 5-Bromospiro[2.4]hepta-4,6-diene-1-carboxylic acid (related to indane system); 5-Bromo-1-carboxyspiro[cyclopropane-2,1'-indane]; 1499315-74-0; 5-Bromo-spiro[cyclopropane-2,1-indane]-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromospiro[Cyclopropane-2,1-Indane]-1-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.