Description

5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-ethyl-1H-pyrazole is a high-value organoboron building block, specifically a pyrazole-substituted cyclic boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules with high fidelity. This compound is critically needed by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring pyrazole motifs.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Research: An essential reagent for academic and industrial laboratories exploring new C-C bond formation methodologies and heterocyclic chemistry.
• Ligand Precursor: Can be utilized to develop novel ligands for catalysis in asymmetric synthesis and transition metal catalysis.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-ethyl-1H-pyrazole
CAS No.	1487356-93-3
Molecular Formula	C11H19BN2O2
Molecular Weight	222.10 g/mol
Synonyms	1-Ethyl-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1H-pyrazole; 1-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (common boronic ester analog); 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-ethylpyrazole; 1-Ethyl-5-(pinacol boronate)pyrazole (related pinacol ester); Ethyl-pyrazole boronic ester, cyclic; B-(1-Ethyl-1H-pyrazol-5-yl)-5,5-dimethyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-ethyl-1H-pyrazole is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.