Description

5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-propyl-1H-pyrazole is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. This compound is critical for modern synthetic chemistry, enabling efficient cross-coupling reactions like Suzuki-Miyaura to construct complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific boronic ester functionalities.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other advanced functional polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for diagnostic and research applications.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis research.
• Ligand & Catalyst Preparation: Used to synthesize novel ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-propyl-1H-pyrazole
CAS No.	1487355-92-9
Molecular Formula	C11H19BN2O2
Molecular Weight	222.10 g/mol
Synonyms	1-Propyl-5-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-1H-pyrazole; 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-propylpyrazole; 1-Propyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (common alternative boronic ester); 1-Propyl-1H-pyrazole-5-boronic acid, pinacol ester; 5-(Pinacolatoboryl)-1-propyl-1H-pyrazole; 1487355-92-9; 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-propyl-1H-pyrazole CAS NO 1487355-92-9
EINECS	Contact for details

Quality Control

Our 5-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-1-propyl-1H-pyrazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our customers in pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Optimal storage temperature is between 2°C and 8°C (refrigerated) for extended stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.