Description

1,2-Piperidinedicarboxylic Acid, 5-Hydroxy-, 1-(1,1-Dimethylethyl) Ester, (2S,5S)- is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique piperidine scaffold and functional groups, which make it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality is crucial for bioactivity.
• Asymmetric Catalysis: Serves as a precursor or ligand for chiral catalysts used in enantioselective synthesis.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new synthetic pathways involving piperidine derivatives.
• Fine Chemical Production: A building block for the manufacture of complex, high-value specialty chemicals beyond the pharmaceutical sector.

Basic Information

Product Name	1,2-Piperidinedicarboxylic Acid, 5-Hydroxy-, 1-(1,1-Dimethylethyl) Ester, (2S,5S)-
CAS No.	1487347-86-3
Molecular Formula	C12H21NO5
Molecular Weight	259.30 g/mol
Synonyms	(2S,5S)-5-Hydroxy-1-(tert-butoxycarbonyl)pipecolic acid; (2S,5S)-1-Boc-5-hydroxypipecolic acid; (2S,5S)-1-(tert-Butoxycarbonyl)-5-hydroxypipecolic acid; 5-Hydroxy-D-pipecolic acid 1-tert-butyl ester; (2S,5S)-1-N-Boc-5-hydroxypipecolic acid; tert-Butyl (2S,5S)-5-hydroxy-1,2-piperidinedicarboxylate; (2S,5S)-5-Hydroxy-1-[(2-methyl-2-propanyl)oxycarbonyl]-2-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1,2-Piperidinedicarboxylic Acid, 5-Hydroxy-, 1-(1,1-Dimethylethyl) Ester, (2S,5S)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (2S,5S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.