Description

(E)-3-(4-Chlorophenyl)-2-Methyl-1-Phenyl-2-Propen-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct α,β-unsaturated ketone structure. This compound serves as a critical pharmaceutical intermediate and a versatile organic building block for advanced chemical synthesis. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, anticancer, or antimicrobial pathways.
• Agrochemical Research: Used as a core scaffold for developing new pesticides, herbicides, and plant growth regulators.
• Organic Synthesis Building Block: Employed in Michael additions, cyclization reactions, and other transformations to create complex heterocyclic compounds.
• Material Science: Investigated as a monomer or cross-linking agent for specialty polymers and advanced organic materials.
• Chemical Biology Probe: Serves as a tool compound for studying biological pathways and protein interactions in research settings.
• Flavor & Fragrance Intermediate: Potential use in the synthesis of complex aroma chemicals.

Basic Information

Product Name	(E)-3-(4-Chlorophenyl)-2-Methyl-1-Phenyl-2-Propen-1-One
CAS No.	1478988-74-7
Molecular Formula	C16H13ClO
Molecular Weight	256.73 g/mol
Synonyms	(E)-3-(4-Chlorophenyl)-2-methyl-1-phenylprop-2-en-1-one; 1-(4-Chlorophenyl)-3-phenyl-2-buten-1-one; 2-Buten-1-one, 1-(4-chlorophenyl)-3-phenyl-; 4'-Chloro-2-methylchalcone; (E)-4'-Chloro-2-methylchalcone; α-Methyl-4-chlorochalcone
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Chlorophenyl)-2-Methyl-1-Phenyl-2-Propen-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.