Description

6-Aza-Spiro[3.4]Octan-7-One is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. Its unique fused-ring structure makes it a critical intermediate for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry: Used as a constrained, three-dimensional building block to explore novel chemical space and improve the pharmacokinetic properties of drug candidates.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and insecticides that require specific stereochemistry for bioactivity.
• Chemical Biology: Utilized as a molecular probe or a core structure in the design of enzyme inhibitors and receptor modulators.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, particularly in spirocycle formation and nitrogen heterocycle chemistry.
• Material Science: Potential precursor for specialty polymers and advanced organic materials with unique properties.

Basic Information

Product Name	6-Aza-Spiro[3.4]Octan-7-One
CAS No.	1465480-75-4
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	6-Azaspiro[3.4]octan-7-one; 7-Azaspiro[3.4]octan-6-one; 1-Azaspiro[3.4]octan-2-one; 6-Aza-spiro[3.4]octan-7-one; Azaspirooctanone; Spirocyclic lactam
EINECS	Contact for details

Quality Control

Our 6-Aza-Spiro[3.4]Octan-7-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Custom synthesis and purification to meet specific project requirements, including GMP standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.