Description

7-Azabicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate and chiral building block. This compound is valued for its rigid, bicyclic scaffold which is integral to the synthesis of complex molecules with specific stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in the areas of neurology and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents.
• Organic Synthesis Building Block: Used to construct complex, nitrogen-containing heterocycles for medicinal chemistry and drug discovery programs.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems.
• Agrochemical Synthesis: Employed in the creation of advanced, biologically active compounds for crop protection.
• Academic & Industrial R&D: A valuable reagent for methodological studies and the synthesis of proprietary chemical libraries.

Basic Information

Product Name	7-Azabicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester Hydrochloride
CAS No.	1461706-04-6
Molecular Formula	C9H16ClNO2
Molecular Weight	205.68 g/mol
Synonyms	Ethyl 7-azabicyclo[2.2.1]heptane-2-carboxylate hydrochloride; 2-Carbethoxy-7-azabicyclo[2.2.1]heptane hydrochloride; 7-Azanorbornane-2-carboxylic acid ethyl ester HCl; 2-Ethoxycarbonyl-7-azabicyclo[2.2.1]heptane hydrochloride; endo-Ethyl 7-azabicyclo[2.2.1]heptane-2-carboxylate hydrochloride; 7-Azabicyclo[2.2.1]heptane-2-carboxylic acid ethyl ester, hydrochloride; Azabicycloheptane carboxylate ester HCl
EINECS	Contact for details

Quality Control

Our 7-Azabicyclo[2.2.1]Heptane-2-Carboxylic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.