Description

Isopropyl 2-(tert-Butoxycarbonyl)-3-(Methylsulfonyloxy)Propanoate is a specialized, high-purity chemical intermediate designed for advanced synthetic applications. This compound is valued for its role as a protected, activated ester, enabling precise and efficient coupling reactions in complex molecule assembly. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide & Amide Bond Formation: Serves as an activated ester reagent for coupling amino acids and other carboxylic acids under mild conditions.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific stereochemistry.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for amines in complex synthetic sequences.
• Process Chemistry & Scale-Up: Suitable for development from laboratory-scale research to pilot plant and commercial manufacturing processes.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.

Basic Information

Product Name	Isopropyl 2-(tert-Butoxycarbonyl)-3-(Methylsulfonyloxy)Propanoate
CAS No.	1456803-29-4
Molecular Formula	C12H22O7S
Molecular Weight	310.36 g/mol
Synonyms	2-[(tert-Butoxy)carbonyl]-3-[(methylsulfonyl)oxy]propanoic Acid Isopropyl Ester; Isopropyl 3-(Methanesulfonyloxy)-2-((tert-butoxycarbonyl)amino)propanoate (common misnomer); Boc-OSu Derivative (contextual); Isopropyl 2-(Boc)-3-(MsO)Propanoate; Propanoic acid, 2-[(1,1-dimethylethoxy)carbonyl]-3-[(methylsulfonyl)oxy]-, 1-methylethyl ester; Activated Boc-Protected Ester
EINECS	Contact for details

Quality Control

Our Isopropyl 2-(tert-Butoxycarbonyl)-3-(Methylsulfonyloxy)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP (current Good Manufacturing Practice) compliance for use in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.