Description

7-Bromo-6-Methyl-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug molecules, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex polyheterocyclic systems due to its reactive bromo and lactam functional groups.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities for clinical trials.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with novel modes of action.

Basic Information

Product Name	7-Bromo-6-Methyl-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One
CAS No.	1456525-53-3
Molecular Formula	C8H7BrN2O2
Molecular Weight	243.06 g/mol
Synonyms	7-Bromo-6-methyl-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-2-one; 7-Bromo-6-methyl-3H-pyrido[2,3-b][1,4]oxazin-2(1H)-one; 7-Bromo-6-methyl-1,2-dihydro-3H-pyrido[2,3-b][1,4]oxazin-3-one; 1456525-53-3; 7-Bromo-6-methylpyrido[2,3-b][1,4]oxazin-2(3H)-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Methyl-1H-Pyrido[2,3-B][1,4]Oxazin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.