Description

5-Bromo-2-(4-Methoxybenzylamino)Nicotinic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1456000-34-2. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core structural component in the multi-step manufacturing of target APIs.
• Biochemical Research: Employed as a tool compound in biochemical assays to study biological pathways and mechanisms of action.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for custom synthesis projects.

Basic Information

Product Name	5-Bromo-2-(4-Methoxybenzylamino)Nicotinic Acid
CAS No.	1456000-34-2
Molecular Formula	C14H13BrN2O3
Molecular Weight	337.17 g/mol
Synonyms	5-Bromo-2-[(4-methoxyphenyl)methylamino]nicotinic acid; 2-[(4-Methoxybenzyl)amino]-5-bromonicotinic acid; Nicotinic acid, 5-bromo-2-[(4-methoxyphenyl)methylamino]-; 5-Bromo-2-(p-methoxybenzylamino)nicotinic acid; 1456000-34-2
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(4-Methoxybenzylamino)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.