Description

6-Bromo-5-Isocyano-Pyridine-2,4-Diamine is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce bromo and isocyano functional groups into pyridine-based scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides due to its reactive bromo and isocyano sites.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of molecular probes and diagnostics.
• Material Science: Incorporated into the design of organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	6-Bromo-5-Isocyano-Pyridine-2,4-Diamine
CAS No.	1452576-93-0
Molecular Formula	C6H4BrN4
Molecular Weight	213.03 g/mol
Synonyms	2,4-Diamino-6-bromo-5-isocyanopyridine; 5-Isocyano-6-bromopyridine-2,4-diamine; 6-Bromo-5-isocyanopyridine-2,4-diyldiamine; 6-Bromo-5-isocyano-2,4-pyridinediamine; 2,4-Pyridinediamine, 6-bromo-5-isocyano-; (6-Bromo-5-isocyanopyridine-2,4-diyl)diamine
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Isocyano-Pyridine-2,4-Diamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.