Description

Potassium 3-Fluoropyridine-4-Trifluoroborate is a versatile organoboron reagent, specifically a potassium trifluoroborate salt, widely used in modern synthetic chemistry. Its core value lies in providing enhanced stability and handling compared to traditional boronic acids, while remaining a highly effective coupling partner. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between pyridine derivatives and aryl/vinyl halides, crucial for constructing complex heterocyclic scaffolds.
• Pharmaceutical Intermediate Synthesis: Serves as a critical building block for the development of active pharmaceutical ingredients (APIs), particularly those containing fluorinated pyridine motifs.
• Agrochemical Compound Development: Used in the synthesis of novel herbicides, fungicides, and insecticides where the 3-fluoropyridine structure imparts desirable biological activity.
• Ligand and Catalyst Preparation: Acts as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Development: Useful for incorporating fluorinated tags into molecules for imaging, diagnostics, and proteomics studies.

Basic Information

Product Name	Potassium 3-Fluoropyridine-4-Trifluoroborate
CAS No.	1451390-70-7
Molecular Formula	C5H3BF4KN
Molecular Weight	206.99 g/mol
Synonyms	Potassium (3-Fluoropyridin-4-yl)trifluoroborate; 3-Fluoropyridine-4-boronic acid potassium trifluoroborate salt; 4-Trifluoroborato-3-fluoropyridine potassium salt; 3-Fluoro-4-pyridyltrifluoroborate potassium; Potassium 3-Fluoro-4-pyridyltrifluoroborate; 3-Fluoropyridin-4-yltrifluoroborate Potassium; Potassium 3-Fluoro-4-(trifluoroboranyl)pyridine
EINECS	Contact for details

Quality Control

Our Potassium 3-Fluoropyridine-4-Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and KF titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (¹H)	≥ 95.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.