Description

3-Chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its fused bicyclic structure, which serves as a privileged scaffold for constructing novel pharmacologically active molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for drug discovery and the development of new active ingredients. Its specific substitution pattern makes it a valuable intermediate for medicinal chemistry programs targeting a range of biological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Scaffold: Serves as a core structure for constructing compound libraries via parallel synthesis for high-throughput screening (HTS).
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides due to its heterocyclic framework.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying enzyme function and protein-protein interactions.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic chemistry and reaction development.
• Custom Synthesis Starting Material: Supplied to contract research organizations (CROs) and custom synthesis manufacturers for client-specific projects.

Basic Information

Product Name	3-Chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-ol
CAS No.	1451184-45-4
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	3-Chloro-2-hydroxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine; 2H-Pyrazolo[1,5-a]pyridin-2-ol, 3-chloro-4,5,6,7-tetrahydro-; 3-Chloro-4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyridin-2-one (tautomer); 3-Chloro-2-oxo-2,4,5,6,7-hexahydropyrazolo[1,5-a]pyridine; CAS 1451184-45-4; Tetrahydropyrazolopyridinol derivative; Chloro-tetrahydropyrazolopyridinol
EINECS	Contact for details

Quality Control

Our 3-Chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-ol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.