Description

(R)-7’-[(R)-Hydroxy(Phenyl)Methyl]-2,2’,3,3’-Tetrahydro-1,1’-Spirobi[Inden]-7-Ol CAS NO 1451057-23-0 is a high-purity, chiral spirobiindane derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block or chiral ligand for the development of novel pharmaceuticals and fine chemicals. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or cardiovascular targets.
• Asymmetric Catalysis: Potential use as a chiral ligand or auxiliary in transition metal-catalyzed reactions to induce high enantioselectivity.
• Advanced Material Research: Investigation as a monomer or functional unit for chiral polymers or liquid crystalline materials with specific optical properties.
• Agrochemical Synthesis: Intermediate for the development of enantiomerically pure herbicides, fungicides, or plant growth regulators.
• Academic & Industrial R&D: Serves as a valuable reference standard and research chemical for method development and exploring new synthetic pathways.

Basic Information

Product Name	(R)-7’-[(R)-Hydroxy(Phenyl)Methyl]-2,2’,3,3’-Tetrahydro-1,1’-Spirobi[Inden]-7-Ol
CAS No.	1451057-23-0
Molecular Formula	C25H24O2
Molecular Weight	356.46 g/mol
Synonyms	(R,R)-7'-(Hydroxy(phenyl)methyl)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7-ol; (R,R)-Spirobiindane-7,7'-diol Derivative; (7R,7'R)-7'-(Hydroxy(phenyl)methyl)-2,2',3,3'-tetrahydrospiro[1H-indene-1,1'-indene]-7-ol; 1,1'-Spirobi[indane]-7,7'-diol, 7'-(hydroxyphenylmethyl)-, (7R,7'R)-; CAS 1451057-23-0; Chiral Spirobiindanol Derivative; (R,R)-SPINOL Derivative Analog.
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to stringent quality protocols. Every batch is characterized and tested to ensure high chemical and chiral purity, with comprehensive analysis via HPLC, NMR, and optical rotation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.