Description

2-(((tert-Butyldimethylsilyl)Oxy)Methyl)Pyrimidine (Wxc04759) is a specialized organosilicon-protected pyrimidine derivative, a key synthetic intermediate in advanced organic chemistry. Its core value lies in providing a robust, orthogonal protecting group for primary alcohols, enabling complex multi-step synthesis with high selectivity and yield. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of nucleoside analogs, active pharmaceutical ingredients (APIs), and other fine chemicals requiring precise molecular manipulation.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer drug discovery.
• Protecting Group Chemistry: Used as a tert-butyldimethylsilyl (TBDMS) protecting agent for hydroxymethyl groups in complex multi-step organic syntheses, offering stability under a wide range of reaction conditions.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides that contain heterocyclic pyrimidine cores.
• Material Science: Potential monomer or modifier in the creation of specialty polymers and functionalized materials with tailored properties.
• Process Chemistry Development: Enables scalable and efficient synthetic routes in pilot plant and commercial manufacturing of high-value fine chemicals.

Basic Information

Product Name	2-(((tert-Butyldimethylsilyl)Oxy)Methyl)Pyrimidine (Wxc04759)
CAS No.	1450643-98-7
Molecular Formula	C11H20N2OSi
Molecular Weight	224.37 g/mol
Synonyms	2-(((tert-Butyldimethylsilyl)oxy)methyl)pyrimidine; Pyrimidine, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-; 2-((tert-Butyldimethylsilyloxy)methyl)pyrimidine; 2-(TBDMS-oxymethyl)pyrimidine; 2-(((TBDMS)O)Methyl)Pyrimidine; WXC-04759; WXC04759; tert-Butyldimethyl((pyrimidin-2-yl)methoxy)silane
EINECS	Contact for details

Quality Control

Our 2-(((tert-Butyldimethylsilyl)Oxy)Methyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.