Description

3-Bromo-4-Pyridinecarboxaldehyde Hydrochloride is a high-purity, versatile chemical building block essential for advanced organic synthesis. This compound is valued for its reactive aldehyde and halogenated pyridine functionalities, enabling precise molecular construction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing new pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Chemistry: The aldehyde group is utilized in condensation reactions to form new heterocyclic systems like imidazoles and quinolines.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry for generating diverse screening libraries.

Basic Information

Product Name	3-Bromo-4-Pyridinecarboxaldehyde Hydrochloride
CAS No.	1449008-16-5
Molecular Formula	C6H5BrClNO
Molecular Weight	222.47 g/mol
Synonyms	3-Bromo-4-formylpyridine hydrochloride; 4-Pyridinecarboxaldehyde, 3-bromo-, hydrochloride; 3-Bromoisonicotinaldehyde hydrochloride; 3-Bromo-4-pyridinecarbaldehyde hydrochloride; 3-Bromo-4-pyridylcarboxaldehyde HCl; 3-Bromo-4-pyridylaldehyde hydrochloride; 3-Bromo-4-pyridinealdehyde hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Pyridinecarboxaldehyde Hydrochloride is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.