Description

2',4'-Dihydro-1'H-Spiro[Oxane-4,3'-Quinoline] is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic quinoline class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Organic Synthesis Building Block: Utilized for constructing complex spirocyclic and fused heterocyclic systems in academic and industrial R&D.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents.

Basic Information

Product Name	2',4'-Dihydro-1'H-Spiro[Oxane-4,3'-Quinoline]
CAS No.	1448855-03-5
Molecular Formula	C12H13NO
Molecular Weight	187.24 g/mol
Synonyms	1'H-Spiro[oxane-4,3'-quinoline], 2',4'-Dihydro-; Spiro[oxane-4,3'-quinoline], 2',4'-dihydro-1'H-; 2,4-Dihydro-1H-spiro[oxane-4,3'-quinoline]; 1448855-03-5; Spirocyclic quinoline derivative; Tetrahydrospiro[chromene-4,4'-piperidine] analogue; Oxaspiroquinoline
EINECS	Contact for details

Quality Control

Our 2',4'-Dihydro-1'H-Spiro[Oxane-4,3'-Quinoline] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.