Description

6-Oxaspiro[4.5]Dec-9-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic amine structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its constrained spirocyclic scaffold.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Chemical Biology: Employed in the development of chemical probes and tool compounds for target validation and biological pathway exploration.
• Custom Synthesis: A valuable substrate for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Oxaspiro[4.5]Dec-9-Ylamine Hydrochloride
CAS No.	1448046-14-7
Molecular Formula	C9H16ClNO
Molecular Weight	189.68 g/mol
Synonyms	9-Amino-6-oxaspiro[4.5]decane hydrochloride; 6-Oxaspiro[4.5]decan-9-amine hydrochloride; Spiro[4.5]decan-9-amine, 6-oxa-, hydrochloride; 6-Oxaspiro[4.5]decan-9-ylamine HCl; 9-Amino-6-oxaspiro[4.5]decane HCl; 1448046-14-7; 6-Oxaspiro[4.5]dec-9-amine HCl
EINECS	Contact for details

Quality Control

Our 6-Oxaspiro[4.5]Dec-9-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.