Description

1,1-Difluorospiro[2.5]Octane-6-Carboxylic Acid is a high-value, structurally complex fluorinated building block. This compound matters as a key intermediate in advanced pharmaceutical and agrochemical research, enabling the introduction of a unique spirocyclic difluoro motif to modulate the physicochemical properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine atoms and spirocyclic structure can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a specialized monomer or additive in the development of advanced polymers with tailored surface properties and chemical resistance.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying new fluorination reactions and the behavior of strained, fluorinated ring systems.

Basic Information

Product Name	1,1-Difluorospiro[2.5]Octane-6-Carboxylic Acid
CAS No.	1447943-49-8
Molecular Formula	C9H12F2O2
Molecular Weight	190.19 g/mol
Synonyms	6-Carboxy-1,1-difluorospiro[2.5]octane; 1,1-Difluoro-6-spiro[2.5]octanecarboxylic acid; Spiro[2.5]octane-6-carboxylic acid, 1,1-difluoro-; Difluorospirooctane carboxylic acid; CAS 1447943-49-8
EINECS	Contact for details

Quality Control

Our production of 1,1-Difluorospiro[2.5]Octane-6-Carboxylic Acid adheres to stringent internal quality standards, ensuring batch-to-batch consistency for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.