Description

Azido-Peg7-Acid CAS NO 1446411-32-0 is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide group at one terminus and a carboxylic acid at the other. This compound is a critical reagent in bioconjugation and click chemistry, enabling the facile and specific coupling of biomolecules, polymers, and surfaces under mild, aqueous conditions. It is essential for researchers and manufacturers in pharmaceuticals, diagnostics, and advanced materials development who require precise and stable cross-linking strategies.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used to link cytotoxic drugs, fluorophores, or other payloads to antibodies, proteins, or peptides via the azide-alkyne cycloaddition (click) reaction.
• PEGylation of Therapeutics: Serves as a functionalized PEG spacer to improve the solubility, stability, and pharmacokinetic profiles of peptide and protein-based drugs.
• Surface Functionalization and Material Science: Employed to modify nanoparticles, biosensors, and hydrogel matrices with bio-recognition elements or other functional groups.
• Polymer Chemistry and Dendrimer Synthesis: Acts as a versatile building block for creating complex, multi-arm PEG architectures and functional polymers.
• Diagnostic Probe Assembly: Facilitates the construction of imaging agents and diagnostic probes by conjugating targeting ligands to reporter molecules.
• Cross-linking Agent: Used to create stable covalent linkages between molecules containing complementary reactive groups (e.g., amines via the carboxylic acid).

Basic Information

Product Name	Azido-Peg7-Acid
CAS No.	1446411-32-0
Molecular Formula	C19H37N3O10
Molecular Weight	467.51 g/mol
Synonyms	Azido-PEG7-acid; 2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic Acid; 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-oic Acid; Azido-PEG7-COOH; N3-PEG7-Acid; Azidoheptaethylene glycol carboxylic acid; Azido-PEG7-propionic acid (common trade name variant); N3-PEG7-COOH
EINECS	Contact for details

Quality Control

Our Azido-Peg7-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and functional group analysis to ensure performance in click chemistry applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting research and GMP-grade manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation and an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Assay (Azide)	≥ 90% of theoretical
Acid Value (Titration)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.