Description

Ald-Peg5-Azide CAS NO 1446282-38-7 is a heterobifunctional polyethylene glycol (PEG) linker featuring an aldehyde group and a terminal azide. This compound is a critical reagent for bioconjugation and click chemistry applications, enabling the precise cross-linking of biomolecules and materials. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science sectors for drug delivery system development, surface functionalization, and the creation of diagnostic probes.

Application

• Bioconjugation reagent for linking peptides, proteins, or antibodies via the aldehyde group to amine-containing molecules.
• Key component in click chemistry reactions, where the azide group reacts with alkynes (e.g., in CuAAC or SPAAC) for labeling and assembly.
• Surface modification and functionalization of nanoparticles, polymers, and solid supports for biomedical applications.
• Synthesis of PEGylated drug conjugates and antibody-drug conjugates (ADCs) to improve pharmacokinetics.
• Preparation of hydrogels and biomaterials with tailored biological properties for tissue engineering.
• Development of diagnostic assays and biosensors through site-specific immobilization of capture molecules.
• Cross-linking agent in polymer chemistry to introduce bio-orthogonal handles into macromolecular structures.
• Tool compound in chemical biology for probing protein interactions and cellular processes.

Basic Information

Product Name	Ald-Peg5-Azide
CAS No.	1446282-38-7
Molecular Formula	C19H37N3O7
Molecular Weight	419.52 g/mol
Synonyms	Azido-PEG5-aldehyde; 5-Azido-3,6,9,12,15-pentaoxaheptadecan-1-al; α-Aldehyde-ω-azido pentaethylene glycol; N3-PEG5-CHO; PEG5-Azide-Aldehyde; Aldehyde-PEG5-Azide; Azido-Pentaethylene glycol-Aldehyde; 1-Azido-3,6,9,12,15-pentaoxaheptadecan-17-al
EINECS	Contact for details

Quality Control

Every batch of Ald-Peg5-Azide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming identity, purity, and functional group integrity via techniques such as NMR, HPLC, and MS. Our quality commitment supports applications in GMP-grade research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Under these conditions, the product is stable for extended periods. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Aldehyde Content (Titration)	≥ 90% of theoretical
Azide Content (IR/Quantitative)	≥ 90% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.