Description

Benzoic Acid, 5-Bromo-2-Ethynyl-, Methyl Ester is a high-purity, specialized organic building block featuring a bromine substituent and an ethynyl group on the aromatic ring. This unique molecular architecture makes it a critical intermediate for advanced synthetic chemistry, enabling the construction of complex molecules through cross-coupling and cycloaddition reactions. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in constructing complex heterocycles and functionalized aromatic systems.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the bromo and ethynyl groups allow for structural diversification and activity optimization.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: A versatile building block for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions in academic and industrial research settings.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	Benzoic Acid, 5-Bromo-2-Ethynyl-, Methyl Ester
CAS No.	1446114-07-3
Molecular Formula	C10H7BrO2
Molecular Weight	239.07 g/mol
Synonyms	5-Bromo-2-ethynylbenzoic acid methyl ester; Methyl 5-bromo-2-ethynylbenzoate; 2-Ethynyl-5-bromobenzoic acid methyl ester; 1446114-07-3; Methyl (5-bromo-2-ethynyl)benzoate; Benzoic acid, 5-bromo-2-ethynyl-, methyl ester; 5-Bromo-2-ethynyl methyl benzoate
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 5-Bromo-2-Ethynyl-, Methyl Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, and spectroscopic identification (NMR, IR). A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC Area %)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.