Description

Carbamic Acid, n-?(4-?Fluoro-?3-?Formyl-?2-?Pyridinyl)?-?, 1,?1-?Dimethylethyl Ester is a specialized fluorinated pyridine derivative that serves as a high-value synthetic intermediate. This compound is critical for enabling precise molecular construction in advanced pharmaceutical and agrochemical research. It is primarily required by R&D chemists and process development scientists working on novel active ingredients, particularly in the fields of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its fluorinated pyridine core.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or molecular probes used in biochemical and cellular assay systems.
• Material Science Research: Potential intermediate for synthesizing specialty polymers or ligands with specific electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	Carbamic Acid, n-?(4-?Fluoro-?3-?Formyl-?2-?Pyridinyl)?-?, 1,?1-?Dimethylethyl Ester
CAS No.	1446091-81-1
Molecular Formula	C12H15FN2O3
Molecular Weight	254.26 g/mol
Synonyms	tert-Butyl N-(4-fluoro-3-formylpyridin-2-yl)carbamate; 2-((tert-Butoxycarbonyl)amino)-4-fluoro-3-pyridinecarboxaldehyde; 4-Fluoro-3-formyl-2-pyridinylcarbamic acid 1,1-dimethylethyl ester; Boc-4F-3-CHO-2-Aminopyridine; (4-Fluoro-3-formyl-pyridin-2-yl)-carbamic acid tert-butyl ester; 2-(Boc-amino)-4-fluoro-3-pyridinecarboxaldehyde; N-Boc-2-amino-4-fluoro-3-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is characterized by modern analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.