Description

1,8-Naphthyridine-3-Carboxylic Acid, 6-Bromo-1,4-Dihydro-4-Oxo-, Ethyl Ester is a high-value brominated naphthyridine derivative that serves as a critical pharmaceutical intermediate and organic building block. This compound is essential for medicinal chemistry research and the synthesis of complex molecules due to its unique heterocyclic structure and reactive bromine substituent. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and antibacterial agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Development: Serves as a building block for creating new active ingredients with herbicidal or pesticidal properties.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of the bromine atom.
• Material Science: Potential component in the development of organic semiconductors or luminescent materials.
• Chemical Biology: Can be used to develop molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	1,8-Naphthyridine-3-Carboxylic Acid, 6-Bromo-1,4-Dihydro-4-Oxo-, Ethyl Ester
CAS No.	1446022-58-7
Molecular Formula	C₁₁H₉BrN₂O₃
Molecular Weight	297.11 g/mol
Synonyms	Ethyl 6-Bromo-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate; 6-Bromo-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid Ethyl Ester; 6-Bromo-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethyl Ester; Ethyl 6-Bromo-4-oxo-1,8-naphthyridine-3-carboxylate; 6-Bromo-1,8-naphthyridin-4(1H)-one-3-carboxylic Acid Ethyl Ester; 1,8-Naphthyridine-3-carboxylic acid, 6-bromo-1,4-dihydro-4-oxo-, ethyl ester; CAS 1446022-58-7
EINECS	Contact for details

Quality Control

Our production of 1,8-Naphthyridine-3-Carboxylic Acid, 6-Bromo-1,4-Dihydro-4-Oxo-, Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.