Description

tert-Butyl 2-oxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new drugs, including potential candidates for neurological and oncological treatments.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules and investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the research and process development of new Active Pharmaceutical Ingredients (APIs), especially those targeting protease inhibition or receptor modulation.
• Contract Manufacturing (CDMO): Supplied to Contract Development and Manufacturing Organizations for cGMP production of clinical trial materials.
• Chemical Biology: Employed in the design and synthesis of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 2-oxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylate
CAS No.	1445951-40-5
Molecular Formula	C15H25N3O3
Molecular Weight	295.38 g/mol
Synonyms	9-Boc-2-oxo-1,4,9-triazaspiro[5.5]undecane; 1,4,9-Triazaspiro[5.5]undecane-9-carboxylic acid, 2-oxo-, 1,1-dimethylethyl ester; tert-Butyl 2-oxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylate; 2-Oxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylic acid tert-butyl ester; Boc-protected 2-oxo-1,4,9-triazaspiro[5.5]undecane; CAS 1445951-40-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-oxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), related substances, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.