Description

tert-Butyl 2-Hydroxy-7-Azaspiro[3.6]Decane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Key Intermediate in Drug Discovery: Serves as a critical building block for synthesizing complex molecules with potential pharmacological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs, especially for targets requiring spirocyclic motifs.
• CNS-Active Compound Synthesis: Applied in the development of potential therapeutics for neurological and psychiatric disorders.
• Protease Inhibitor Development: The structural features make it relevant for creating inhibitors of specific enzymes.
• Custom Synthesis & Scale-Up: Supplied for process research and development (PR&D) and pilot-scale manufacturing of active pharmaceutical ingredients (APIs).
• Academic & Industrial R&D: Utilized in exploratory chemistry to access novel chemical space for biological screening.

Basic Information

Product Name	tert-Butyl 2-Hydroxy-7-Azaspiro[3.6]Decane-7-Carboxylate
CAS No.	1445951-30-3
Molecular Formula	C14H25NO3
Molecular Weight	255.35 g/mol
Synonyms	7-Boc-2-Hydroxy-7-Azaspiro[3.6]decane; tert-Butyl 2-hydroxy-7-azaspiro[3.6]decane-7-carboxylate; 2-Hydroxy-7-azaspiro[3.6]decane-7-carboxylic acid tert-butyl ester; 7-(tert-Butoxycarbonyl)-2-hydroxy-7-azaspiro[3.6]decane; 7-Azaspiro[3.6]decane-7-carboxylic acid, 2-hydroxy-, 1,1-dimethylethyl ester; 1445951-30-3; Boc-Protected 2-Hydroxy-7-Azaspiro[3.6]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Hydroxy-7-Azaspiro[3.6]Decane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.