Description

2-tert-Butyl 9-Ethyl 8-Oxo-2,7-Diazaspiro[4.4]Nonane-2,9-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic diaza structure. This compound is of significant value in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and optimization of new therapeutic agents.

Application

• Key Intermediate in Drug Discovery: Serves as a critical building block for the synthesis of spirocyclic compounds with potential pharmacological activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical space and optimize lead compounds.
• Protease Inhibitor Development: The diazaspiro[4.4]nonane core is a privileged scaffold in the design of inhibitors for various enzymes.
• Pre-clinical Pharmaceutical Development: Employed in the synthesis of compounds for biological screening and pre-clinical evaluation stages.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.

Basic Information

Product Name	2-tert-Butyl 9-Ethyl 8-Oxo-2,7-Diazaspiro[4.4]Nonane-2,9-Dicarboxylate
CAS No.	1445951-14-3
Molecular Formula	C16H26N2O5
Molecular Weight	326.39 g/mol
Synonyms	tert-Butyl 9-ethyl 8-oxo-2,7-diazaspiro[4.4]nonane-2,9-dicarboxylate; 2,7-Diazaspiro[4.4]nonane-2,9-dicarboxylic acid, 8-oxo-, 2-(1,1-dimethylethyl) 9-ethyl ester; 8-Oxo-2,7-diazaspiro[4.4]nonane-2,9-dicarboxylic acid 2-tert-butyl 9-ethyl ester; 1445951-14-3; CAS 1445951-14-3
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 9-Ethyl 8-Oxo-2,7-Diazaspiro[4.4]Nonane-2,9-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.