Description

2-tert-Butyl 5-Methyl 7-Oxa-2-Azaspiro[3.5]Nonane-2,5-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for constructing complex molecular architectures with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Building Block: Used to introduce the constrained 7-oxa-2-azaspiro[3.5]nonane moiety into lead compounds to modulate physicochemical properties and biological activity.
• Process Chemistry: Employed in route scouting and optimization for the scalable synthesis of target molecules during API development.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and protein function.
• Agrochemical Research: Potential application as an intermediate in the synthesis of novel crop protection agents with new modes of action.

Basic Information

Product Name	2-tert-Butyl 5-Methyl 7-Oxa-2-Azaspiro[3.5]Nonane-2,5-Dicarboxylate
CAS No.	1445950-84-4
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	tert-Butyl 5-methyl 7-oxa-2-azaspiro[3.5]nonane-2,5-dicarboxylate; 2-(tert-Butoxycarbonyl)-5-(methoxycarbonyl)-7-oxa-2-azaspiro[3.5]nonane; 7-Oxa-2-azaspiro[3.5]nonane-2,5-dicarboxylic acid, 2-(1,1-dimethylethyl) 5-methyl ester; Boc-Protected 7-Oxa-2-azaspiro[3.5]nonane Methyl Ester; Spirocyclic Oxazolidinone Ester Intermediate
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl 5-Methyl 7-Oxa-2-Azaspiro[3.5]Nonane-2,5-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.