Description

7-Oxospiro[3.5]Nonane-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic ketone-carboxylic acid structure. This compound is valued for its role as a critical building block in the synthesis of complex, bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for constructing novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex spirocyclic scaffolds in active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore new chemical space and structure-activity relationships (SAR).
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component due to its rigid, three-dimensional structure and functional handles.
• Chemical Biology Probes: Utilized in the synthesis of tool compounds for target identification and validation studies.
• Asymmetric Synthesis: Acts as a chiral precursor or template for the development of enantioselective catalysts or ligands.
• Academic & Institutional R&D: Employed in fundamental organic synthesis research and methodology development.

Basic Information

Product Name	7-Oxospiro[3.5]Nonane-2-Carboxylic Acid
CAS No.	1440962-16-2
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	7-Oxospiro[3.5]nonane-2-carboxylic acid; 2-Carboxy-7-oxospiro[3.5]nonane; Spiro[3.5]nonane-2-carboxylic acid, 7-oxo-; 7-Oxospiro(3.5)nonane-2-carboxylic Acid; 1440962-16-2; 7-Oxaspiro[3.5]nonane-2-carboxylic acid (common misnomer); 2-Carboxyspiro[3.5]nonan-7-one
EINECS	Contact for details

Quality Control

Our 7-Oxospiro[3.5]Nonane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.