Description

3-Pyridinol,6-Chloro-4-(4-Fluoro-1H-Indol-2-Yl) is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Oncology Drug Discovery: Serves as a core scaffold for developing kinase inhibitors and other targeted cancer therapies.
• CNS-Active Compound Synthesis: Used in research programs focused on creating novel compounds for neurological and psychiatric disorders.
• Chemical Biology & Proteomics: Employed as a molecular probe or tagging agent in biochemical research to study protein-ligand interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and scale-up activities.
• Academic Research: Utilized in university and institutional labs for methodological development in synthetic organic and medicinal chemistry.

Basic Information

Product Name	3-Pyridinol,6-Chloro-4-(4-Fluoro-1H-Indol-2-Yl)
CAS No.	1440544-97-7
Molecular Formula	C13H8ClFN2O
Molecular Weight	262.67 g/mol
Synonyms	6-Chloro-4-(4-fluoro-1H-indol-2-yl)pyridin-3-ol; 4-(4-Fluoro-1H-indol-2-yl)-6-chloropyridin-3-ol; 6-Chloro-4-(4-fluoroindol-2-yl)-3-pyridinol; 2-(6-Chloro-3-hydroxypyridin-4-yl)-4-fluoro-1H-indole; CAS 1440544-97-7
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinol,6-Chloro-4-(4-Fluoro-1H-Indol-2-Yl) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.