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1-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)-2,2,2-Trichloroethanone CAS NO 1440535-48-7


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CAS No.:1440535-48-7

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Description

1-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)-2,2,2-Trichloroethanone is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value in medicinal chemistry for constructing complex molecular architectures, particularly in the development of new therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel bioactive compounds, including kinase inhibitors and other targeted small-molecule drugs.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and CNS research.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
  • Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways and protein functions.
  • Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
  • Material Science: Investigated as a precursor for specialty chemicals and functional materials due to its halogenated structure.

Basic Information

Product Name 1-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)-2,2,2-Trichloroethanone
CAS No. 1440535-48-7
Molecular Formula C9H4BrCl3N2O
Molecular Weight 358.40 g/mol
Synonyms 1-(6-Bromoimidazo[1,2-a]pyridin-3-yl)-2,2,2-trichloroethanone; 2,2,2-Trichloro-1-(6-bromoimidazo[1,2-a]pyridin-3-yl)ethanone; 6-Bromo-3-(trichloroacetyl)imidazo[1,2-a]pyridine; 1440535-48-7; Trichloro(6-bromoimidazo[1,2-a]pyridin-3-yl)methanone
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Quality Control

Our 1-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)-2,2,2-Trichloroethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive and should be handled accordingly.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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