Description

[4-(3-Methylpyridin-2-Yl)Oxan-4-Yl]Methanamine is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines pyridine and oxane (tetrahydropyran) ring systems. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged heterocyclic structure.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Ligand Synthesis: Can be utilized to create complex ligands for catalysis or biochemical probes.
• Academic & Institutional R&D: Used in university and research institute laboratories for exploratory synthetic and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis organizations (CSOs) and CDMOs serving the global pharmaceutical pipeline.

Basic Information

Product Name	[4-(3-Methylpyridin-2-Yl)Oxan-4-Yl]Methanamine
CAS No.	1439896-86-2
Molecular Formula	C12H18N2O
Molecular Weight	206.28 g/mol
Synonyms	4-[(3-Methyl-2-pyridinyl)oxy]tetrahydro-2H-pyran-4-methanamine; 4-((3-Methylpyridin-2-yl)oxy)tetrahydro-2H-pyran-4-yl)methanamine; 4-(3-Methylpyridin-2-yloxy)tetrahydropyran-4-ylmethanamine; 2-((4-(Aminomethyl)tetrahydro-2H-pyran-4-yl)oxy)-3-methylpyridine; (4-((3-Methylpyridin-2-yl)oxy)tetrahydro-2H-pyran-4-yl)methanamine; 4-(Aminomethyl)-4-((3-methylpyridin-2-yl)oxy)tetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our [4-(3-Methylpyridin-2-Yl)Oxan-4-Yl]Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your R&D and regulatory documentation needs. We adhere to cGMP principles where applicable to ensure consistent batch-to-batch quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.