Description

tert-Butyl n-{6-Oxaspiro[2.5]Octan-1-Yl}Carbamate is a specialized spirocyclic building block and protected amine intermediate of significant interest in advanced organic synthesis. Its unique oxaspiro[2.5]octane scaffold provides a rigid, three-dimensional framework that is highly valuable for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity and improved environmental profiles.
• Advanced Material Science: Serves as a precursor for functionalized monomers or ligands in the creation of specialty polymers and metal-organic frameworks (MOFs).
• Methodology Development: Employed in academic and industrial research to develop new synthetic methodologies involving strained ring systems and protected functional group manipulations.
• Peptidomimetics & Bioisosteres: The oxaspiro[2.5]octane unit can act as a conformationally restricted bioisostere for peptide bonds or other molecular fragments in drug design.

Basic Information

Product Name	tert-Butyl n-{6-Oxaspiro[2.5]Octan-1-Yl}Carbamate
CAS No.	1439896-66-8
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	1-N-Boc-6-Oxaspiro[2.5]octane; tert-Butyl 6-Oxaspiro[2.5]octane-1-carboxylate; 6-Oxaspiro[2.5]octane-1-carboxylic acid, 1,1-dimethylethyl ester; Boc-6-Oxaspiro[2.5]octane; N-Boc-6-Oxaspiro[2.5]octan-1-amine; (6-Oxaspiro[2.5]octan-1-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-{6-Oxaspiro[2.5]Octan-1-Yl}Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to supply reliability and traceability supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is stable under inert atmosphere but should be protected from prolonged exposure to strong bases and moisture. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.