Description

2-(5-Methoxypyridin-2-Yl)-2-Methylpropanoic Acid is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its unique pyridine-based structure, which serves as a critical scaffold in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the methoxypyridine moiety can enhance biological activity and selectivity.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Academic and Industrial R&D: Utilized in research laboratories for methodological studies, structure-activity relationship (SAR) exploration, and process chemistry optimization.
• Material Science: Potential application as an organic component in the development of advanced functional materials and electronic chemicals.

Basic Information

Product Name	2-(5-Methoxypyridin-2-Yl)-2-Methylpropanoic Acid
CAS No.	1439896-55-5
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	2-(5-Methoxy-2-pyridinyl)-2-methylpropanoic acid; 2-Methyl-2-(5-methoxypyridin-2-yl)propanoic acid; α,α-Dimethyl-5-methoxypicolinic acid; 5-Methoxy-2-(2-carboxypropan-2-yl)pyridine; 2-(5-Methoxypyridin-2-yl)-2-methylpropionic acid; 1439896-55-5; UNII-9F3V8VK3QN
EINECS	Contact for details

Quality Control

Our production of 2-(5-Methoxypyridin-2-Yl)-2-Methylpropanoic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay, impurity profile, and residual solvents. Our quality system is designed to support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.