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(1R)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol CAS NO 1435948-36-9


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CAS No.:1435948-36-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a high-purity, chiral spirobiindane derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block or chiral ligand for the development of pharmaceuticals and specialty materials, offering a rigid, three-dimensional framework. It is primarily needed by research and development teams in pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and catalysts.

Application

  • Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
  • Asymmetric Catalysis: Used as a ligand or core structure for developing novel chiral catalysts in enantioselective synthesis.
  • Material Science Research: Acts as a monomer or building block for creating chiral polymers and advanced organic frameworks (MOFs/COFs).
  • Agrochemical Development: Employed in the research phase for synthesizing new, stereospecific active ingredients for crop protection.
  • Academic & Industrial R&D: Utilized in chemical research for studying structure-activity relationships (SAR) and novel reaction pathways.

Basic Information

Item Details
Product Name (1R)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No. 1435948-36-9
Molecular Formula C17H14I2O2
Molecular Weight 528.10 g/mol
Synonyms (1R)-6,6'-Diiodospirobiindane-7,7'-diol; (1R)-Spirobiindane-7,7'-diol, 6,6'-diiodo-2,2',3,3'-tetrahydro-; (R)-6,6'-Diiodo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol; 6,6'-Diiodo-(1R)-spirobiindane-7,7'-diol; (1R)-6,6'-Diiodo-2,2',3,3'-tetrahydrospirobi[indene]-7,7'-diol; (R)-enantiomer of 6,6'-Diiodospirobiindane-7,7'-diol
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Quality Control

Our (1R)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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