Description

Trimethylsilyl Nonafluoropentanoate is a specialized organofluorine and organosilicon compound used as a key reagent and intermediate in advanced chemical synthesis. Its value lies in the unique combination of the perfluorinated alkyl chain, which imparts high stability and specific physicochemical properties, and the trimethylsilyl group, which acts as a versatile protecting and activating moiety. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing fluorinated active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of fluorinated drug candidates, leveraging the metabolic stability and lipophilicity of the perfluorobutyl group.
• Agrochemical Synthesis: Serves as a building block for creating novel fluorinated pesticides and herbicides with enhanced activity and environmental persistence.
• Surface Modification Agent: Imparts oil-, water-, and stain-repellent characteristics to textiles, polymers, and coatings.
• Advanced Material Precursor: A key monomer or modifier in the production of specialty fluorosilicones and high-performance polymers.
• Analytical Chemistry Reagent: Employed in derivatization techniques for gas chromatography (GC) or mass spectrometry (MS) to improve the volatility and detection of analytes.
• Lithography and Electronics: Potential use in the formulation of photoresists or as a precursor for depositing fluorine-containing thin films in semiconductor manufacturing.

Basic Information

Product Name	Trimethylsilyl Nonafluoropentanoate
CAS No.	1435806-43-1
Molecular Formula	C8H9F9O2Si
Molecular Weight	336.23 g/mol
Synonyms	Nonafluoropentanoic Acid Trimethylsilyl Ester; Trimethylsilyl Perfluoropentanoate; 4,4,5,5,6,6,7,7,7-Nonafluoroheptanoic Acid Trimethylsilyl Ester; TMS Nonafluoropentanoate; (Perfluorobutyl)acetic Acid Trimethylsilyl Ester; 2,2,3,3,4,4,5,5,5-Nonafluoropentanoic Acid Trimethylsilyl Ester; C4F9CH2COOSi(CH3)3; Heptadecafluorononanoic Acid Trimethylsilyl Ester (common misnomer)
EINECS	Contact for details

Quality Control

Our Trimethylsilyl Nonafluoropentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are provided and can be tailored to meet the requirements of cGMP, ISO, or other relevant quality frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. This compound is hygroscopic (moisture-sensitive) and highly volatile; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening and allowed to equilibrate to room temperature before use to prevent moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.