Description

Methyl 2-(3,3-Difluorocyclobutyl)Acetate is a high-value fluorinated building block and ester derivative, distinguished by its unique cyclobutyl core and difluoro substitution. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, where its structure imparts desirable physicochemical properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the metabolically stable difluorocyclobutyl moiety.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorinated cyclobutane structure can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and coatings with tailored properties like chemical resistance or low surface energy.
• Ligand and Catalyst Development: Employed in the synthesis of complex organic ligands and catalysts for asymmetric synthesis and other specialized chemical transformations.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on exploring the effects of fluorination and strained ring systems in molecular design.

Basic Information

Product Name	Methyl 2-(3,3-Difluorocyclobutyl)Acetate
CAS No.	1434141-84-0
Molecular Formula	C8H12F2O2
Molecular Weight	178.18 g/mol
Synonyms	Methyl (3,3-Difluorocyclobutyl)acetate; Acetic acid, 2-(3,3-difluorocyclobutyl)-, methyl ester; 2-(3,3-Difluorocyclobutyl)acetic acid methyl ester; Methyl 3,3-difluorocyclobutan-1-ylacetate; (3,3-Difluorocyclobutyl)acetic acid methyl ester; Methyl difluorocyclobutylacetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(3,3-Difluorocyclobutyl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) against established internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.