Description

(S)-Methyl 3-Methylmorpholine-3-Carboxylate Hydrochloride is a high-purity chiral building block of significant importance in modern synthetic chemistry. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs). Pharmaceutical research and development organizations, particularly those focused on neurology, oncology, and antiviral therapies, need this material for its role in creating novel, potent, and selective drug candidates.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Used as a building block to introduce the morpholine scaffold with a defined (S)-configuration into target molecules, enabling enantioselective synthesis.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for commercial drug manufacturing.
• Ligand and Catalyst Preparation: Potential precursor for the synthesis of chiral ligands or organocatalysts used in asymmetric transformations.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(S)-Methyl 3-Methylmorpholine-3-Carboxylate Hydrochloride
CAS No.	1434126-95-0
Molecular Formula	C8H15NO3 • HCl
Molecular Weight	209.67 g/mol
Synonyms	Methyl (3S)-3-methylmorpholine-3-carboxylate hydrochloride; (S)-Methyl 3-methylmorpholine-3-carboxylate HCl; (3S)-3-Methylmorpholine-3-carboxylic acid methyl ester hydrochloride; (S)-3-Methylmorpholine-3-carboxylic acid methyl ester hydrochloride; Methyl (S)-3-methylmorpholine-3-carboxylate hydrochloride; 1434126-95-0; (S)-3-Methyl-3-morpholinecarboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Methyl 3-Methylmorpholine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.