Description

Methyl 4-Bromo-3-Chloro-5-(Trifluoromethoxy)Benzoate is a high-purity, multi-functional aromatic ester building block designed for advanced chemical synthesis. Its complex halogenated and trifluoromethoxy-substituted structure makes it a critical intermediate for developing novel active compounds in the pharmaceutical and agrochemical sectors. This product is essential for research and development chemists and process engineers seeking to introduce specific steric and electronic properties into target molecules. Its reliable quality ensures consistent results in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of new drug candidates with complex aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and trifluoromethoxy groups contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for creating specialized polymers and liquid crystals with unique thermal and optical properties.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-catalyzed transformations to construct complex molecular architectures.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 4-Bromo-3-Chloro-5-(Trifluoromethoxy)Benzoate
CAS No.	1433280-61-5
Molecular Formula	C9H5BrClF3O3
Molecular Weight	333.49 g/mol
Synonyms	Methyl 4-bromo-3-chloro-5-(trifluoromethoxy)benzoate; Benzoic acid, 4-bromo-3-chloro-5-(trifluoromethoxy)-, methyl ester; 4-Bromo-3-chloro-5-(trifluoromethoxy)benzoic acid methyl ester; Methyl 4-bromo-3-chloro-5-[(trifluoromethyl)oxy]benzoate; CAS 1433280-61-5
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Bromo-3-Chloro-5-(Trifluoromethoxy)Benzoate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support compliance with cGMP and ISO 9001 standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.