Description

Ethyl 4-Chloro-2-Formylpyridine-3-Carboxylate is a high-value pyridine derivative and a versatile chemical building block. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides due to its reactive aldehyde and ester functional groups.
• Ligand and Catalyst Development: Serves as a starting material for creating complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing specialty chemicals and advanced materials.
• Academic and Industrial Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Ethyl 4-Chloro-2-Formylpyridine-3-Carboxylate
CAS No.	1433204-33-1
Molecular Formula	C9H8ClNO3
Molecular Weight	213.62 g/mol
Synonyms	Ethyl 4-chloro-2-formylnicotinate; 4-Chloro-2-formylpyridine-3-carboxylic acid ethyl ester; 3-Pyridinecarboxylic acid, 4-chloro-2-formyl-, ethyl ester; Ethyl 4-chloro-2-pyridinecarboxylate-5-carboxaldehyde; 4-Chloro-2-formylnicotinic acid ethyl ester; 2-Formyl-4-chloronicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2-Formylpyridine-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. All products are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.