Description

2-(Aminomethyl)Pyridin-4-Ol Hydrochloride is a high-purity organic salt derivative of pyridine, serving as a critical building block in advanced chemical synthesis. Its bifunctional structure, featuring both an amino and a hydroxyl group on the pyridine ring, makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting the central nervous system.
• Agrochemical Synthesis: Building block for creating advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to prepare chelating ligands for metal catalysts in asymmetric synthesis and polymerization processes.
• Bioconjugation and Linker Chemistry: The reactive amine and hydroxyl groups facilitate its use in creating chemical linkers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Material Science Research: Intermediate in the production of functionalized polymers and organic electronic materials.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D for exploring new synthetic pathways.

Basic Information

Product Name	2-(Aminomethyl)Pyridin-4-Ol Hydrochloride
CAS No.	1432754-63-6
Molecular Formula	C6H9N2O·HCl
Molecular Weight	160.61 g/mol (Free base: 124.15 g/mol)
Synonyms	4-Hydroxy-2-(aminomethyl)pyridine hydrochloride; 2-(Aminomethyl)-4-hydroxypyridine hydrochloride; 2-(Aminomethyl)-4-pyridinol hydrochloride; 4-Pyridinol, 2-(aminomethyl)-, hydrochloride; (4-Hydroxy-2-pyridinyl)methanamine hydrochloride; 2-Pyridinemethanamine, 4-hydroxy-, hydrochloride; 4-Hydroxy-2-pyridinemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Aminomethyl)Pyridin-4-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and heavy metals. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with the specifications required for research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent moisture uptake and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.