Description

5-Azaspiro[2.4]heptane-5,6-dicarboxylic Acid, 5-(1,1-Dimethylethyl) 6-Ethyl Ester is a high-value, advanced pharmaceutical intermediate characterized by its unique spirocyclic and azetidine ring structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with improved metabolic stability and target selectivity. It is primarily needed by R&D teams and process chemists in the pharmaceutical and biotechnology industries for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of complex molecules in drug discovery programs.
• Protease Inhibitor Synthesis: Used in the research and development of protease inhibitors for treating viral infections.
• Building Block for Bioactive Molecules: Serves as a versatile scaffold for creating libraries of compounds with potential neurological or anti-inflammatory activity.
• Chemical Biology Research: Employed as a tool compound or a labeled precursor in mechanism-of-action studies.
• Process Chemistry & Scale-up: Utilized in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical development.

Basic Information

Product Name	5-Azaspiro[2.4]heptane-5,6-dicarboxylic Acid, 5-(1,1-Dimethylethyl) 6-Ethyl Ester
CAS No.	1432754-14-7
Molecular Formula	C14H23NO4
Molecular Weight	269.34 g/mol
Synonyms	5-tert-Butyl 6-ethyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate; 5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) 6-ethyl ester; tert-Butyl ethyl 5-azaspiro[2.4]heptane-5,6-dicarboxylate; Azetidine-spirocyclopropane dicarboxylate derivative; Spiro[2.4]heptane intermediate; CAS 1432754-14-7
EINECS	Contact for details

Quality Control

Our production of 5-Azaspiro[2.4]heptane-5,6-dicarboxylic Acid, 5-(1,1-Dimethylethyl) 6-Ethyl Ester adheres to strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Any individual impurity ≤1.0%
Total Impurities	≤3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.