Description

1,8-Diazaspiro[4.5]Decane, 1-Methyl-, Hydrochloride (1:2) is a high-purity, spirocyclic amine salt building block of significant interest in advanced organic synthesis. Its unique constrained bicyclic structure makes it a valuable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its spirocyclic amine scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where its structural motif can impart specific biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the development of specialty polymers with unique thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	1,8-Diazaspiro[4.5]Decane, 1-Methyl-, Hydrochloride (1:2)
CAS No.	1432679-85-0
Molecular Formula	C9H18N2 · 2HCl
Molecular Weight	239.18 g/mol
Synonyms	1-Methyl-1,8-diazaspiro[4.5]decane dihydrochloride; 1-Methyl-1,8-diazaspiro[4.5]decane hydrochloride (1:2); 1-Methyl-1,8-diazaspiro[4.5]decane bis(hydrochloride); 1-Methyl-1,8-diazaspiro[4.5]decane dihydrochloride salt; 1-Methyl-1,8-diazaspiro[4.5]decan-1-ium chloride hydrochloride; Spirocyclic amine salt; 1-Methyl-1-azonia-8-azaspiro[4.5]decane dichloride
EINECS	Contact for details

Quality Control

Our 1,8-Diazaspiro[4.5]Decane, 1-Methyl-, Hydrochloride (1:2) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.