Description

Cyclohexane Cyanine7 NHS ester is a near-infrared (NIR) fluorescent labeling reagent designed for the covalent conjugation of biomolecules. This compound is critical for researchers and developers requiring high-sensitivity detection and imaging in complex biological systems. It is primarily used by professionals in the pharmaceutical, biotechnology, and life science research sectors for applications such as antibody labeling, protein tracking, and in vivo imaging.

Application

• Antibody-Dye Conjugate Synthesis: For creating fluorescently labeled antibodies used in flow cytometry, immunohistochemistry (IHC), and Western blotting.
• Protein & Peptide Labeling: Enables the tracking of protein-protein interactions, cellular uptake studies, and enzyme activity assays.
• In Vivo Imaging Probes: A key component in developing NIR fluorescent probes for non-invasive deep-tissue imaging in preclinical research.
• Nucleic Acid Labeling: Used for labeling oligonucleotides and other nucleic acid analogs for sensitive detection in hybridization assays.
• Diagnostic Kit Development: Integral to the formulation of high-performance diagnostic assays and kits requiring stable, bright NIR signals.
• Polymer & Nanoparticle Functionalization: For attaching fluorescent tags to drug delivery vehicles, biosensors, and other advanced materials.

Basic Information

Product Name	Cyclohexane Cyanine7 NHS ester
CAS No.	1432019-64-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cy7 NHS ester (Cyclohexane); Sulfo-Cy7 NHS ester (Cyclohexane); Cyanine7 carboxylic acid N-hydroxysuccinimide ester (Cyclohexane); 1-(5-Carboxypentyl)-2-((1E,3E)-5-(1-(5-carboxypentyl)-3,3-dimethyl-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-ium-5-sulfonate NHS ester; NIR Dye NHS ester; Cy7.5 NHS ester analog; Heptamethine cyanine NHS ester
EINECS	Contact for details

Quality Control

Our Cyclohexane Cyanine7 NHS ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive life science applications. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance, fluorescence, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Absorption (λmax)	~750 - 780 nm
Emission (λmax)	~770 - 800 nm
Extinction Coefficient	Contact for details
Solubility	Soluble in DMSO, DMF, and other polar aprotic solvents
Moisture Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.